中国药物警戒 ›› 2018, Vol. 15 ›› Issue (2): 73-77.

• 利巴韦林临床使用调查分析专栏 • 上一篇    下一篇

基于鄞州区域医疗数据的利巴韦林临床使用的分析

林鸿波1, 刘翠丽2, 沈鹏1, 李海龙3, 赵厚宇3, 詹思延3,*   

  1. 1 宁波市鄞州区疾病预防控制中心，浙江 宁波 315100;
    2 国家食品药品监督管理局药品评价中心，北京 100045;
    3 北京大学公共卫生学院流行病与卫生统计系，北京 100191
  • 收稿日期:2017-09-25 修回日期:2018-03-28 出版日期:2018-02-20 发布日期:2018-03-28
  • 通讯作者: 詹思延，女，教授?博导，药物流行病学。E-mail: siyan-zhan@bjmu.edu.cn
  • 作者简介:林鸿波，男，主任医师，慢性病预防与控制。

Analysis of Ribavirin Utilization Based on Yinzhou Healthcare Database

LIN Hong-bo1, LIU Cui-li2, SHEN Peng1, LI Hai-long3, ZHAO Hou-yu3, ZHAN Si-yan3,*   

  1. 1 Yinzhou District Center for Disease Control and Prevention, Zhejiang Ningbo 315100, China;
    2 Center for Drug Revaluation, CFDA, Beijing 100045, China;
    3 Department of Epidemiology and Bio-statistics, School of Public Health, Peking University, Beijing 100191, China
  • Received:2017-09-25 Revised:2018-03-28 Online:2018-02-20 Published:2018-03-28

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摘要： 目的 描述宁波市鄞州区医疗机构门诊利巴韦林的使用情况。方法 利用鄞州区医疗卫生信息数据库对3家综合性医院，24家社区卫生服务中心在2010年至2016年期间利巴韦林门诊使用情况进行分析。结果 研究期间，鄞州区医疗机构门诊中利巴韦林处方量为1587 504次，使用人数为673 661，其中利巴韦林注射液和粉针处方数占97.74%。利巴韦林处方主要由一级医疗机构开出，处方次数和人数呈逐年减少趋势。14岁及以下儿童处方人次数约占总处方数的50.56%。患者用药原因主要为急性上呼吸道感染，约占总处方数的68.85%。结论 利巴韦林处方仍存在不合理，尤其对于注射剂临床上使用应该进一步规范处方适应证，密切关注治疗情况。

关键词: 利巴韦林, 数据库, 药物利用, 合理用药

Abstract: Objective To describe the clinical utilization of ribavirin in Ningbo city, Yinzhou District. Methods We conducted a descriptive analysis of the clinical utilization of ribavirin in 3 general hospitals and 24 community health centers from 2010 to 2016 by using Yinzhou healthcare information database. Results During the study period, we found 1587 504 outpatients' prescriptions of ribavirin and 673,661 ribavirin users. Ribavirin injections accounted for 97.74% of all ribavirin prescriptions. In addition, ribavirin was mainly prescribed by primary grade medical institutions. The result showed the number of prescriptions and users of ribavirin was decreasing. Moreover, ribavirin prescriptions of children (≤14) accounted for 50.56% of the total number of ribavirin prescriptions. Among all ribavirin prescriptions, there were 68.85% recorded diagnosis of acute upper respiratory tract infection. Conclusion The results indicated that there were large amount of irrational prescriptions of ribavirin. Clinicians should adhere to the indication of ribavirin injection and pay attention to the treatment.

Key words: ribavirin, database, drug utilization, rational drug use

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