350例儿科住院患者的抗菌药物临床应用分析

中国药物警戒 ›› 2017, Vol. 14 ›› Issue (9): 559-561.

350例儿科住院患者的抗菌药物临床应用分析

张琳¹, 杨波², 王来成^3*

1 徐州市第一人民医院药剂科,江苏徐州 221002;
2 徐州市食品药品监督管理局,江苏徐州 221018;
3 徐州医科大学附属医院药学部,江苏徐州 221006

收稿日期:2017-11-06 修回日期:2017-11-06 出版日期:2017-09-20 发布日期:2017-11-06
通讯作者: 王来成,男,本科,主任药师,临床药学。E-mail：wanglch6419@163.com
作者简介:张琳,女,本科,副主任药师,医院药学。

Analysis of 350 Cases of Antimicrobial Agents Clinical Use in Pediatric Inpatients

ZHANG Lin¹, YANG Bo², WANG Lai-cheng^3,*

1 Department of Pharmacy, First People′s Hospital of Xuzhou, Jiangsu Xuzhou 221002, China;
2 Xuzhou Food and Drug Administration, Jiangsu Xuzhou 221018, China;
3 Department of Pharmacy, Hospital Affiliated to Xuzhou Medical University, Jiangsu Xuzhou 221006, China

Received:2017-11-06 Revised:2017-11-06 Online:2017-09-20 Published:2017-11-06

摘要/Abstract

摘要： 目的了解我院儿科住院患者抗菌药物使用情况,评价其临床应用合理性,为临床合理用药提供参考依据。方法利用医院HIS系统抽取2016年1~6月份使用抗菌药物的归档住院病历350份。统计分析抗菌药物使用品种、给药频次、联合用药及病原学送检等。结果单一使用抗菌药物128例,占36.57%;二联用药222例,占63.43%;病原学送检率为33.14%,品种选择以青霉素类、头孢菌素类及大环内酯类为主。结论儿科住院患者抗菌药物使用较合理,抗菌药物使用起点过高、给药频次过低、联用比例较高,非感染性疾病无指征使用抗菌药物等不合理现象,仍需采取有效干预措施,进一步促进临床合理用药。

关键词: 儿科, 住院患者, 抗菌药物, 合理用药

Abstract: Objective To investigate the application of antibacterial agents in pediatric inpatients in our hospital and evaluate the rationality to provide references for clinic. Methods 350 outpatients' medical records were selected randomly by HIS from January to June in 2016. The indexes in terms of antibacterial selection, frequency of medication, combination therapy and pathogenic examination were analyzed. Results 128 cases were treated with one kind of antibiotics and the ratio was 36.57%. 222 cases were treated with combination use of antibiotics and the ratio was 63.43%. The inspection ratio of pathogenic bacteria was 33.14%. Penicillins, cephalosporins, and macrolides ranked top 3 in terms of use frequency. Conclusion Clinical management of the use of antibacterials is mainly rational, but the irrational administration of antibiotics in pediatric outpatients is still present in terms of drug selection, combination therapy, frequency of medication and improper drug selection. The supervision of using antibiotics should be highlighted to enhance the clinical management of rational use of antibacterials.

Key words: pediatric, inpatients, antibiotics, rational drug use

中图分类号:

R969.3

张琳, 杨波, 王来成. 350例儿科住院患者的抗菌药物临床应用分析[J]. 中国药物警戒, 2017, 14(9): 559-561.

ZHANG Lin, YANG Bo, WANG Lai-cheng. Analysis of 350 Cases of Antimicrobial Agents Clinical Use in Pediatric Inpatients[J]. Chinese Journal of Pharmacovigilance, 2017, 14(9): 559-561.

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