中国药物警戒 ›› 2010, Vol. 7 ›› Issue (10): 623-625.

• 药品不良反应监测 • 上一篇    下一篇

170例参麦注射液不良反应文献分析

黎颖然1 潘泰先2   

  1. 1.中山市人民医院,广东中山528400；
    2.广东药学院,广东中山528400
  • 收稿日期:2010-04-29 修回日期:2016-03-12 出版日期:2010-10-08 发布日期:2016-03-09
  • 作者简介:黎颖然,女,主管药师,临床药学。

Analysis of 170 Cases on Adverse Drug Reaction of Shenmai Injection

LI Ying-ran1, PAN Tai-xian2   

  1. 1.Zhongshan People's Hospital, Guangdong Zhongshan 528400, China;
    2.Guangdong Pharmaceutical University, Guangdong Zhongshan 528400, China
  • Received:2010-04-29 Revised:2016-03-12 Online:2010-10-08 Published:2016-03-09

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摘要： 目的 探讨参麦注射液不良反应的规律及特点,为临床合理用药提供参考。方法 收集中山市人民医院2008～2009 年上报广东省药品不良反应（ADR）监测中心的参麦注射液不良反应的病例,检索1994～2009 年国内公开发行的医学期刊报道的应用参麦注射液后发生不良反应的病例,进行统计分析。结果 参麦注射液不良反应多发生于40 岁以上年龄组,女性多于男性,其ADR 出现时间多在用药过程中30min 内发生。不良反应临床表现复杂多样,以过敏反应居多。结论 临床医师、药师应重视参麦注射液的不良反应,加强其应用过程中的监测,谨慎用药。

关键词: 参麦注射液, 药品不良反应（ADR）, 分析

Abstract: Objective To explore the general rule and the characteristics of adverse drug reaction(ADR) induced by Shenmai injection and to provide some references for clinical medicine and rational use of drug. Methods One part of the ADR reports were collected by Zhongshan People's Hospital of 2008 to 2009, another part of the reports were collected by national journals of 1994 to 2009. 170 ADR则eports were analyzed using retrospective study method. Results ADR appeared mostly in the 40 age group, and more in female. The onset of ADR was usually within the first 30 min during the infusion. and the clinical manifestations of ADR were various, of which the allergic reaction was the most common. Conclusion Doctors and pharmacists should pay more attention to the ADR of Shenmai injection for the Immediate allergic reaction.

Key words: Shenmai injection, adverse drug reaction(ADR), analysis

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