中国药物警戒 ›› 2013, Vol. 10 ›› Issue (4): 241-243.

• 药械安全性研究 • 上一篇    下一篇

51例阿立哌唑的不良反应/事件分析

尉秀峰1, 徐作国1*,黄河亮1,丛娟2   

  1. 1.烟台市心理康复医院,山东莱阳265200；
    2.莱阳市食品药品监督管理局,山东 莱阳265200
  • 收稿日期:2012-08-29 修回日期:2016-03-09 出版日期:2013-04-08 发布日期:2016-03-09
  • 通讯作者: 徐作国,男,副主任医师,精神科临床和药品不良反应监测工作。E-mail: xuzuoguo@126.com
  • 作者简介:尉秀峰,男,本科,副主任医师,精神疾病司法鉴定。

Analysis of 51 Cases of Adverse Reactions/Events of Aripiprazole

WEI Xiu-feng1 ,XU Zuo-guo1, HUANG He-liang1 ,CONG Juan2   

  1. 1.Psycho-rehabilitation Hospital of Yantai, Shandong Laiyang 265200, China;
    2.Food and Drug Administration of Laiyang, Shandong Laiyang 265200, China
  • Received:2012-08-29 Revised:2016-03-09 Online:2013-04-08 Published:2016-03-09

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摘要： 目的 探讨阿立哌唑的不良反应/事件,为临床安全用药提供参考。方法 搜集两家精神疾病类杂志近几年刊登的有关阿立哌唑药品不良反应的病例报告15 例,同时收集临床中不良反应病例36 例,进行统计与分析。结果 阿立哌唑不良反应/ 事件累及9 大系统- 器官,涉及22 种表现。以肝胆系统、锥体外系统、血液系统、心血管系统较多见。88.24%的不良反应/ 事件在30 天内发生,急性不良反应者较少。结论 阿立哌唑不良反应/ 事件以肝胆系统、锥体外系统、血液系统、心血管系统较多,急性不良反应较少,为较理想的抗精神病药物。

关键词: 阿立哌唑, 不良反应/事件

Abstract: Objective To investigate aripiprazole adverse reactions/events, provide a reference for clinical safety of drugs. Methods We Searched two types of magazimes on mental illness in recent years, 15 cases of aripiprazole adverse reaction reports were collected, together with 36 clinical cases of adverse reactions, acomprehensive statistical analysis waconducted. Results Aripiprazole adverse reactions/events involve 9 systems -organs, including 22 manifestations. The hepatobiliary system, extrapyramidal system, blood system and cardiovascular system were more commonly involved. 88.24% of the adverse reactions occurred within 30 days, acute adverse reactions were less. Conclusion Aripiprazole adverse reactions/events commonly involved the hepatobiliary system, extrapyramidal system and blood system and cardiovascular system, fewer acute adverse reactions occurred. It is an ideal antipsychotic drug.

Key words: aripiprazole, adverse reaction/event

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