中国药物警戒 ›› 2010, Vol. 7 ›› Issue (8): 498-499.

• 药品不良反应监测 • 上一篇    下一篇

104例抗菌药物不良反应/事件报告分析

李国誉, 林红宁   

  1. 肇庆市第一人民医院药剂科,广东 肇庆 526021
  • 收稿日期:2016-02-22 修回日期:2016-02-22 出版日期:2010-08-08 发布日期:2016-02-22
  • 作者简介:李国誉,男,药师,临床药学与药品不良反应监测。

Analysis of 104 Cases of Adverse Drug Reaction Reports of Antibacterial Agents

LI Guo-yu, LIN Hong-ning   

  1. Dept.of Pharmacy, Zhaoqing First People's Hospital, Guangdong Zhaoqing 526021, China
  • Received:2016-02-22 Revised:2016-02-22 Online:2010-08-08 Published:2016-02-22

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摘要： 目的 了解和分析抗菌药物发生不良反应/事件的大致情况,为临床合理使用抗菌药物提供依据和参考。方法 对我市某医院2009年104例抗菌药物所致不良反应/事件报告进行分析。结果 104例不良反应/事件报告中,女性略多于男性;18~59岁年龄段的成年患者占多数;以静脉滴注给药为主（72例,占69.23%）;以头孢菌素类发生不良反应的例数最多（40例,占38.46%）;不良反应的类型以皮肤及其附件损害最常见（54例,占51.92%）。结论 医疗机构应重视抗菌药物的不良反应,加强抗菌药物临床应用的监管。

关键词: 抗菌药物, 药品不良反应/事件

Abstract: Objective To investigate the situation of adverse drug reaction/event(ADR/ADE) of antibacterial agents, thus to provide bases and references for rational use of antibacterial agents． Methods 104 ADR reports of antibacterial agentswere collected and analyzed in a hospital during 2009． Result Of the total 104 ADR reports, females was slightly more than males; adult patients between 18 to 59 years old age were accounted for the majority; 72 cases that administered intravenously were accounted for the majority(69.23%); the cases that caused by cephalosporins were accounted for the most(40 cases,38.46%), and damage to the skin and accessories(54 cases, 51.92%)was the commonest type． Conclusion We should pay great attention to the ADR of antibacterial agents, and strengthen the supervision of clinical application of antibacterial agents．

Key words: antibacterial agents, adverse drug reaction/event(ADR/ADE)

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