中国药物警戒 ›› 2010, Vol. 7 ›› Issue (4): 217-220.

• 管理研究 • 上一篇    下一篇

PASS监测用药风险警示的评估及成因分析

郭代红1, 杜晓曦2*, 陈珲1, 张素敏2, 刘皈阳1, 张素琼2, 陈超1, 董放2, 史国兵3, 张勤4   

  1. 1解放军总医院药品保障中心,北京 100853;
    2国家食品药品监督管理局药品评价中心;
    3沈阳军区总医院,辽宁 沈阳 110016;
    4成都军区总医院,四川 成都 610083
  • 收稿日期:2016-02-19 修回日期:2016-02-19 出版日期:2010-04-08 发布日期:2016-02-19
  • 通讯作者: 杜晓曦,女,研究员,课题负责人,药品评价与药品不良反应监测。E-mail:duxiaoxi@cdr.gov.cn
  • 作者简介:郭代红,女,硕士生导师,临床药学与药事管理。
  • 基金资助:
    国家食品药品监督管理局药品评价中心国家科技支撑计划课题 “安全用药关键技术研究与应用” （课题编号2006BAI4B04）子课题

Factor Analyse and Risk Vigilance Evaluate of PASS Used Monitoring Prescription

GUO Dai-hong1, DU Xiao-xi2,*, CHEN Hui1, ZHANG Su-min2, LIU Gui-yang1, ZHANG Su-qiong2, CHEN Chao1, DONG Fang2, SHI Guo-bing3, ZHANG Qin4   

  1. 1Department of Pharmaceutic care, Chinese PLA General Hospital, Beijing 100853;
    2Center of Drug Reevaluation, SFDA Beijing 100045;
    3Shenyang General Hospital of PLA, Liaoning Shenyang 110016;
    4Chengdu General Hospital of PLA,Sichuan Chengdu 610083
  • Received:2016-02-19 Revised:2016-02-19 Online:2010-04-08 Published:2016-02-19

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摘要： 目的 了解PASS监测系统在临床治疗中的警示作用并进行溯源评估。方法 采用病例观察方法,通过PASS系统对2008年5~12月间3所医院科室的住院医嘱进行监测,评价警示信息有效性并作关联性因素分析。采用SPSS软件进行数据统计分析。结果 4 910例患者的29 700条医嘱中,重点警示信息2 813条,主要集中于药物相互作用、特殊人群、配伍禁忌、给药剂量、给药途径;其中有效的1 161条信息的关联性因素以人员因素为最多;无效的1 652条则主要源自PASS的局限性。结论 PASS因其智能化有限,临床存在闯关提交医嘱现象;但用于临床短时大量医嘱的快速初审人工无法替代,其警示信息对于提示临床医师预见并规避可能的风险隐患方面有显著的实用意义。

关键词: PASS, 警示, 风险规避, 成因分析

Abstract: Objective Analying of influence factor and evaluating of vigilance effection of PASS used monitoring pre-scription. Methods Using case investigating method. Screenning some inpatient prescription of three hospital during May to December in 2008 by PASS, Evaluating vigilance effection and analyse influence factor. The correlative data were deal with the SPSS software. Results There were 2 813 piece of stress vigilance information in 29 700 prescription of 4 910 cases, Concentrated in five representation-interaction, special patient, no-no mix, dosage and approach. Effective 1 161 piece by reason of personnel, and the other 1 652 piece are restricted by PASS itself. Conclusion Using PASS to monitor prescription have distinct practicality for rational drug use. Its vigilance information can remind doctor to avoid the risk about drug safety.

Key words: PASS, vigilance, risk elusion, factor analysis

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