中国药物警戒 ›› 2010, Vol. 7 ›› Issue (1): 48-51.

• 药品不良反应监测 • 上一篇    下一篇

178例中药不良反应/事件分析

刘洋, 朱蓓*, 郭桂明   

  1. 首都医科大学附属北京中医医院,北京 100010
  • 收稿日期:2009-07-31 修回日期:2016-02-18 出版日期:2010-01-08 发布日期:2016-02-18
  • 通讯作者: *通讯作者：朱蓓,女,主任药师,临床药学。E-mail:zhubei3061@163.com
  • 作者简介:刘洋,女,硕士研究生,临床药学。

Retrospective Analysis of 178 Traditional Chinese Medicine ADR/ADE Reports

LIU Yang, ZHU Bei*, GUO Gui-ming   

  1. The Pharmacy Department,BeiJing Hospital of Traditional Chinese Medicine Affiliated to the Capital University of Medical Science, Beijing 100010, China
  • Received:2009-07-31 Revised:2016-02-18 Online:2010-01-08 Published:2016-02-18

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摘要： 目的 分析我院中药的使用状况及不良反应/事件发生特点,探讨不良反应/事件发生的相关因素。方法 采用回顾性分析方法,对我院2006年1月至2008年8月搜集的178例中药不良反应报告进行统计分析。结果 178例中药不良反应报告中,共涉及药品105种,其中,96例发生在用药1小时以内（53.93%）。主要不良反应/事件的临床表现为皮肤及其附件损害;发生频率排前3位均为中药注射剂;中成药的新的不良反应/事件99例（55.62%）;严重不良反应11例;引起严重不良反应的药物以口服药居多。结论 加强中药不良反应/事件的监控力度,提高临床合理用药水平,保障患者用药安全。

关键词: 中药, 不良反应/事件, 合理用药

Abstract: Objective Analyzed serious adverse drug reaction/event（ADR/ADE） of traditional Chinese medicine（TCM） occurred in our hospital and discuss the related factors of ADR/ADE. Methods 178 ADR reports of TCM collected by our hospital from JUN.2006 to AUG.2008 were analyzed using retrospective study method. Results Amo-ng the 178 ADR/ADE reports, 105 kinds of drugs were involved in different dosage forms and specifications, 96（53.93%） ADR reports were happened in one hour. skin and its adjunct is likely to be the most affected organ. the top three of occurrence frequency in ADR/ADE were injections; and the reports of new ADR/ADE caused by Chi-nese patent medicine is 99（55.62%）. 11 severe adverse reactions were occurred, and oral drugs accounted for a higher proportion.Conclusion ADR monitoring should be strengthened to improve the rational use of drug.

Key words: traditional Chinese medision（TCM）, adverse drug reaction/event（ADR/ADE）, rational use of drug

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