院外延伸药学服务对心梗患者PCI术后的预后及用药依从性的影响

中国药物警戒 ›› 2018, Vol. 15 ›› Issue (8): 485-488.

院外延伸药学服务对心梗患者PCI术后的预后及用药依从性的影响

王明蕾¹, 王芳^{2 *}

¹威海市中心医院药剂科,山东威海 264400;
²常州市金坛区人民医院中心药房,江苏常州 213200

收稿日期:2018-10-11 修回日期:2018-10-11 出版日期:2018-08-20 发布日期:2018-10-11
通讯作者: 王芳,女,本科,主管药师,临床药学。E-mail：waves929@126.com
作者简介:王明蕾,男,本科,主管中药师,药学。

Effects of Out-hospital Extended Pharmaceutical Intervention in Myocardial Infarction Patients after PCI on Prognosis and Medication Compliance

WANG Minglei¹, WANG Fang^2*

¹Department of Pharmacy, Weihai Central Hospital, Shandong Weihai 264400, China;
²Department of Central Pharmacy, Jintan District People's Hospital of Changzhou, Jiangsu Changzhou 213200, China

Received:2018-10-11 Revised:2018-10-11 Online:2018-08-20 Published:2018-10-11

摘要/Abstract

摘要： 目的探讨院外延伸药学服务对心梗患者经皮冠状动脉介入治疗（PCI）的预后情况以及药物依从性的影响。方法选取2014年3月至2017年5月入我院接受PCI治疗的心肌梗死患者160例,80例接受院外延伸药学服务,80例作为对照组,比较两组患者出院1年后在预后情况以及服药依从性的差异。结果两组患者一般资料比较差异无统计学意义（P >0.05）,实验组药物依从性高于对照组,依从人数显著高于对照组,部分依从人数低于对照组（P <0.05）。预后方面,对照组患者LVEDV高于实验组患者,LVEF和E/A低于实验组患者,差异具有统计学意义（P <0.05）,心血管不良事件发生人数对照组高于实验组,其中再次血运重建和心力衰竭人数显著高于实验组,差异具有统计学意义（P <0.05）。结论出院后院外延伸药学服务可提高患者用药依从性,减少心血管事件发生几率并且改善心梗患者PCI术后的预后情况。

关键词: 院外延伸药学服务, 心梗, 药物依从性, 预后

Abstract: Objective To investigate the effects of out-hospital extended pharmaceutical intervention on medication compliance and prognosis of myocardial infarction patients after PCI. Methods 160 myocardial infarction patients after percutaneous coronary intervention (PCI) treated in our hospital during Mar 2014 to May 2017 were selected and divided into control group (with 80 patients) and test group (with 80 patients under out-hospital extended pharmaceutical intervention). Prognosis and medication compliance after 1 year discharge between the two groups were compared. Results General data of the two groups had no significant differences between the two groups(P >0.05). LVEDV of control group was higher than test group, LVEF and E/A of control group was lower than test group and the differences were significant (P <0.05). The drug compliance of the test group was higher than that of the control group, the number of compliance was significantly higher than that of the control group, and the number of partial compliance was lower than that of the control group (P <0.05). On the part of prognosis, more patients of control group had cardiovascular adverse events than test group. Among these events, incidences of control group of revascularization and heart failure were significantly higher than test group, which was significantly higher than control group (P<0.05). Conclusion Out-hospital extended pharmaceutical intervention can improve medication compliance and reduce the incidence of cardiac events of myocardial infarction patients after PCI.

Key words: out-hospital extended pharmaceutical intervention, myocardial infarction, medication compliance, prognosis

中图分类号:

R972

王明蕾, 王芳. 院外延伸药学服务对心梗患者PCI术后的预后及用药依从性的影响[J]. 中国药物警戒, 2018, 15(8): 485-488.

WANG Minglei, WANG Fang. Effects of Out-hospital Extended Pharmaceutical Intervention in Myocardial Infarction Patients after PCI on Prognosis and Medication Compliance[J]. Chinese Journal of Pharmacovigilance, 2018, 15(8): 485-488.

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