中国药物警戒 ›› 2013, Vol. 10 ›› Issue (3): 148-150.

• 药械质量研究 • 上一篇    下一篇

朝鲜苍术挥发油成分GC-MS分析

姚慧娟1,姚慧敏2,卜书红1, 陆晓彤1,张健1   

  1. 1.上海交通大学医学院附属新华医院药剂科,上海200092；
    2.通化师范学院吉林省长白山药用植物研究重点实验室,吉林通化134002
  • 收稿日期:2012-11-07 修回日期:2016-03-09 出版日期:2013-03-08 发布日期:2016-03-09
  • 作者简介:姚慧娟,女,硕士,药理学。

Analysis of the Volatile Oil Constituent of Atractylodes Coreana (Nakai)Kitam by GC-MS

YAO Hui-juan1,YAO Hui-min2, BU Shu-hong1, LU Xiao-tong1, ZHANG Jian1   

  1. 1.Xinhua Hospital Affiliated to the Medicine College of Shanghai Jiaotong University, Shanghai 200092, China;
    2.Key Laboratory of Changbai Mountain Medicinal Plants Research of Tonghua Normal University, Jilin Tonghua 134002 , China
  • Received:2012-11-07 Revised:2016-03-09 Online:2013-03-08 Published:2016-03-09

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摘要： 目的 研究朝鲜苍术挥发油成分,为朝鲜苍术的药用价值及合理开发利用提供参考。方法 采用水蒸气蒸馏法提取挥发油,GC 毛细管柱色谱法进行分析,峰面积归一化法确定其相对含量,气相色谱- 质谱联用技术辅助人工检索鉴定其化学成分。结果 从朝鲜苍术的挥发油中分离出58 种,鉴定出55 种化学成分,鉴定出的挥发性化学成分占挥发油总量的79.94 %,主要成分有苍术酮（31.1831 %）、3- 羟基-6 β- 环丙烷-5 β- 胆甾烷（12.3086 %）、5 -螺甾烷（11.2161%）、巴伦西亚橘烯（7.05606%）、γ- 榄香烯（4.24732 %）、菜油甾醇（2.11089 %）、石竹烯（1.44473 %）、- 桉叶烯（1.43541 %）、9,10- 脱水-异长叶烯（1.21445 %）、α- 石竹烯（0.72132 %）。结论 朝鲜苍术挥发油的主要化学成分为倍半萜类化合物。

关键词: 朝鲜苍术, 水蒸气蒸馏法, 挥发油, 气相色谱-质谱法

Abstract: Objective To analyze the volatile oil constituent of . Methods The volatile oil was extracted by steam distillation, analyzed by capillary GC. The relative content of chemical components was calculated by peak area normalization method, the chemical components were identified by gas chromatography mass spectrometry. Results We found that 58 components were isolated, 55 components were identified, the identified chemical components account for 79.94 % of the total volatile oil, including 1,2-Bis -[4-pyridine -N -oxide]ethane (31.1831%)、[5,6]cholestan -3 -ol,3',6 -dihydro-, (3.beta.,5.beta.,6.alpha.) -Cyclopropa (12.3086 %)、5 α-Spirostan (11.2161%)、1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-,[1R-(1.alpha.,7.beta.,8a.alpha.)]Naphthalene(7.05606%)、 γ-Elemene(4.24732%)、8(14)-en-3-ol,(3.beta.)-Ergost(2.11089%)、Caryophyllene(1.44473%)、decahydro -4a -methyl -1 -methylene -7 -(1 -methylethenyl) -, [4aR -(4a.alpha.,7.alpha.,8a.beta.)] -Naphthalene (1.43541%)、9,10-dehydro-isolongifolene(1.21445%)、α-Caryophyllene(0.72132%). Conclusion We concluded that the main chemical components of . volatile oil are sesquiterpenoids.

Key words: steam distillation, volatile oil, gas chromatography mass spectrometry

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