中国药物警戒 ›› 2012, Vol. 9 ›› Issue (7): 385-386.

• 临床研究 •    下一篇

玻璃酸钠联合复方倍他米松治疗创伤性膝关节滑膜炎临床疗效分析

牛树真   

  1. 山东省东营市东营区牛庄镇卫生院,山东 东营 257086
  • 收稿日期:2012-03-01 出版日期:2012-07-10 发布日期:2015-08-07
  • 作者简介:牛树真,女,主管药师, 药理学。

Clinical Efficacy Analysis on Sodium Hyaluronate Combined with Compound Betamethasone in Treatment of Traumatic Synovitis of Knee Joint

NIU Shu-zhen   

  1. Niuzhuang Town Hospital of Dongying District, Dongying City of Shandong Province, Shandong Dongying 257086, China
  • Received:2012-03-01 Online:2012-07-10 Published:2015-08-07

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摘要： 目的观察玻璃酸钠联合复方倍他米松膝关节腔内注射方法对创伤性膝关节滑膜炎的临床治疗效果。方法76例创伤性膝关节滑膜炎患者随机分为两组,试验组患者进行每周1次,连续5周膝关节腔内注射,第1、3周同时注射玻璃酸钠和复方倍他米松（非糖皮质激素禁忌证患者）两种药物,2、4、5周,仅注射玻璃酸钠,而对照组仅给予玻璃酸钠膝关节腔内注射,每周1次,连续5周。观察治疗前后膝关节疼痛、肿胀、关节积液程度。结果试验组在膝关节疼痛的缓解和膝关节功能的改善方面均优于对照组。结论玻璃酸钠联合复方倍他米松膝关节腔内注射是治疗创伤性膝关节滑膜炎安全、有效的方法,尤其适合早、中期的创伤性膝关节滑膜炎患者,是一种值得推广的方法。

关键词: 玻璃酸钠, 复方倍他米松, 关节腔内注射, 创伤性膝关节滑膜炎

Abstract: ObjectiveTo observe the clinical efficacy of sodium hyaluronate combined with compound betamethasone on the treatment of traumatic synovitis of knee joint under the method of knee articular cavity injection. Methods76 cases of traumatic synovitis of knee joint were randomly divided into two groups, the test group patients were given knee articular cavity injection once a week for 5 weeks, and sodium hyaluronate and compound betamethasone were given simultaneously during the 1st and 3rd week, only sodium hyaluronate was given during the 2nd, 4th and 5th week. Whereas the control group only received knee articular cavity injection of sodium hyaluronate once a week for 5 weeks. Observed the knee joint pain, swelling and joint effusion before and after treatment. ResultsThe relief of knee joint pain and improvement of knee joint function in test group were better than those in control group. ConclusionSodium hyaluronate combined with compound betamethasone by knee articular cavity injection is a safe and effective method for the treatment of traumatic synovitis of knee joint, especially for the patients with early or medium-term traumatic synovitis of knee joint, it is worthy to be recommended.

Key words: sodium hyaluronate, compound betamethasone, intra articular injection, traumatic synovitis of knee joint