中国药物警戒 ›› 2021, Vol. 18 ›› Issue (2): 196-198.
DOI: 10.19803/j.1672-8629.2021.02.21

• 安全与合理用药 • 上一篇    下一篇

膦甲酸钠注射液致周身麻木、呼吸困难1例分析

刘洋, 马春华, 梁连春*   

  1. 首都医科大学附属北京佑安医院感染综合科,北京 100069
  • 收稿日期:2020-01-06 修回日期:2021-02-26 出版日期:2021-02-15 发布日期:2021-02-26
  • 通讯作者: *梁连春,男,主任医师,新发传染病与感染性疾病的发病机制与临床特征的研究。E-mail: llc671215@sohu.com
  • 作者简介:刘洋,女,硕士,主治医师,中医学。

Cace Analysis of General Numbness and Dyspnea Caused by Foscarnet Sodium for Injection

LIU Yang, MA Chunhua, LIANG Lianchun*   

  1. Department of General Infection, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
  • Received:2020-01-06 Revised:2021-02-26 Online:2021-02-15 Published:2021-02-26

摘要: 目的 探讨膦甲酸钠导致周身麻木、呼吸困难的机制及相关文献分析。方法 我院既往诊治1例肝衰竭合并巨细胞感染患者,在应用膦甲酸钠时出现周身麻木及呼吸困难等症状,通过文献分析,探讨其发生机制,并结合该病例阐述膦甲酸钠相关不良反应概况。结果 膦甲酸钠可导致周身麻木、呼吸困难,其机制可能与低钙血症相关。结论 膦甲酸钠应用中应严密监测患者情况,及时发现并处理不良反应。

关键词: 膦甲酸钠, 麻木, 药品不良反应

Abstract: Objective To explore the mechanism of foscarnet sodium causing general numbness and dyspnea and to analyze the related literature. Methods A case of liver failure with cytomegalovirus infection was diagnosed and treated in our hospital. The symptoms of numbness and dyspnea occurred during the application of foscarnet sodium. Through literature analysis, the mechanism of the occurrence of foscarnet sodium related adverse reactions was discussed. Results Foscarnet sodium could cause general numbness and dyspnea, which might be related to hypocalcemia. Conclusion During the application of foscarnet sodium, the patients should be closely monitored, and adverse reactions should be found and treated in time.

Key words: foscarnet sodium, numbness, adverse drug reaction

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