中国药物警戒 ›› 2021, Vol. 18 ›› Issue (1): 77-79.
DOI: 10.19803/j.1672-8629.2021.01.15

• 安全与合理用药 • 上一篇    下一篇

8例替加环素致低钙血症不良反应分析

陶宏, 沈珠, 曹国文*, 施爱明, 潘杰   

  1. 苏州大学附属第二医院药剂科,江苏 苏州 215004
  • 收稿日期:2019-11-12 修回日期:2021-01-18 出版日期:2021-01-15 发布日期:2021-01-18
  • 通讯作者: *曹国文,男,本科,副主任药师,临床药学。E-mail:sdfecaoguowen@sina.com
  • 作者简介:陶宏,男,本科,主管药师,临床药学。

Eight Cases of Hypocalcemia Induced by Tigecycline

TAO Hong, SHEN Zhu, CAO Guowen*, SHI Aiming, PAN Jie   

  1. Department of Pharmacy,the Second Affiliated Hospital of Soochow University,Suzhou Jiangsu 215004,China
  • Received:2019-11-12 Revised:2021-01-18 Online:2021-01-15 Published:2021-01-18

摘要: 目的 提高临床使用替加环素的安全性。方法 借助于某三甲医院2018年7月1日至2019年6月30日不良反应主动监测软件筛选使用替加环素发生低钙血症的患者,结合电子病历和药品不良反应判定标准对数据进行分析。结果 使用替加环素与发生低钙血症相关。结论 建议临床使用替加环素时,应加强对血钙的监测。

关键词: 替加环素, 低钙血症, 药品不良反应

Abstract: Objective To improve the safety of clinical use of tigecycline.Methods Patients with hypocalcemia caused by tigecycline were screened from July 1,2018 to June 30,2019 with active monitoring software for adverse reactions before data was analyzed using electronic medical records and adverse reaction criteria.Results The use of tigecycline was associated with hypocalcemia.Conclusion It is recommended that the monitoring of serum calcium be enhanced when tigecycline is used in clinic.

Key words: tigecycline, hypocalcemia, adverse drug reaction

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