烟酸注射液药品不良反应报告分析

doi:10.19803/j.1672-8629.2020.12.13

中国药物警戒 ›› 2020, Vol. 17 ›› Issue (12): 907-912.
DOI: 10.19803/j.1672-8629.2020.12.13

烟酸注射液药品不良反应报告分析

张纾¹, 林强^{1, *}, 邓文², 陈深³

¹福建省药品不良反应监测中心,福建福州 350002;
²福州市医疗保障数据监测中心,福建福州 350005;
³福州市药品不良反应监测中心,福建福州 350014

收稿日期:2020-06-03 修回日期:2020-12-07 出版日期:2020-12-15 发布日期:2020-12-07
通讯作者: ^*林强,女,硕士,主任药师,药品不良反应监测与评价。E-mail:908121385@qq.com
作者简介:张纾,女,硕士,主管药师,药品不良反应监测与评价。

Adverse Drug Reactions of Nicotinic Acid Injection

ZHANG Shu¹, LIN Qiang^1*, DENG Wen², CHEN Shen³

¹Center for ADR Monitoring of Fujian,Fuzhou Fujian 350002,China;
²Fuzhou Health Care Security Data Monitoring Center,Fuzhou Fujian 350005,China;
³Center for ADR Monitoring of Fuzhou,Fuzhou Fujian 350014,China

Received:2020-06-03 Revised:2020-12-07 Online:2020-12-15 Published:2020-12-07

摘要/Abstract

摘要： 目的分析烟酸注射液药品不良反应(ADR)的发生规律及特点,为其临床合理用药提供参考。方法对2017年1月1日至2019年12月31日福建省上报国家药品不良反应监测系统的1 174例烟酸注射液药品不良反应/事件(ADR/AE)报告进行分析。结果烟酸注射液ADR发生时间多集中在用药过程中,药品不良反应以过敏反应和血管扩张相关的反应为主,主要表现为皮肤及其附件损害、血管损害和全身性损害等。结论应加强烟酸注射液的临床用药监测,及时修订完善药品说明书,促进合理用药,保障患者用药安全。

关键词: 烟酸注射液, 药品不良反应, 合理用药

Abstract: Objective To analyze the characteristics and regularity of adverse drug reactions (ADR) caused by nicotinic acid injection in order to provide reference for clinical rational drug use.Methods The 1 174 ADR/AE of reported to the ADRS by fujian Province between January 2017 and December 2019 were analyzed using the retrospective study method.Results ADRs caused by nicotinic acid injection mostly occurred in the process of medication. These ADRs were mostly allergic reactions and angiectasis reactions and manifested themselves as the damage to the skin and its accessories, vascular damage and systemic damage.Conclusion We should strengthen the clinical monitoring of nicotinic acid injection, update the drug labeling without delay and promote the rational use of medicines so as to ensure the safety of medication.

Key words: nicotinic acid injection, adverse drug reactions, rational use of drugs

中图分类号:

R994.11

张纾, 林强, 邓文, 陈深. 烟酸注射液药品不良反应报告分析[J]. 中国药物警戒, 2020, 17(12): 907-912.

ZHANG Shu, LIN Qiang, DENG Wen, CHEN Shen. Adverse Drug Reactions of Nicotinic Acid Injection[J]. Chinese Journal of Pharmacovigilance, 2020, 17(12): 907-912.

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烟酸注射液药品不良反应报告分析

Adverse Drug Reactions of Nicotinic Acid Injection

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